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Extraintestinal manifestations and characteristics of ulcerative colitis in Xinjiang Uygur Autonomous Region / 中华消化杂志
Chinese Journal of Digestion ; (12): 818-822, 2018.
Artigo em Chinês | WPRIM | ID: wpr-734990
ABSTRACT
Objective To analyze the extraintestinal manifestations and clinical characteristics of patients with ulcerative colitis (UC) and to improve the knowledge,diagnosis and treatment of UC with extraintestinal manifestations.Methods From January 2013 to December 2017,at the Department of Gastroenterology,People's Hospital of Xinjiang Uygur Autonomous Region,260 hospitalized patients diagnosed as UC were collected.The demographic characteristics,clinical phenotypes and extraintestinal manifestations were analyzed.Chi square test was used for statistical analysis.Results Among 260 UC patients,41.9% (109/260) had extraintestinal manifestations,including fatty liver (17.3%,45/260),gallbladder stone (11.9%,31/260),type Ⅰ peripheral arthritis (8.1%,21/260),type Ⅱ peripheral arthritis (3.1%,8/260),oral ulcer (4.6 %,12/260),erythema nodosum (3.8%,10/260),irireitis (1.9%,5/260),ankylosing spondylitis (1.5%,4/260),sacroiliitis (1.5%,4/260),pyoderma gangrenosum (0.4%,1/260) and primary sclerosing cholangitis (0.4%,1/260).Gender,ethnicity,age,history of intestinal surgery and body mass index (BMI) could affect the occurrence of extraintestinal manifestations in patients with UC (x2 =7.901,4.318,9.291,8.162 and 10.397,all P<0.05).The incidence of joint lesions in Uygur UC patients was higher than that in Han UC patients (16.6 %,24/145 vs.7.0%,8/115),and the difference was statistically significant (x2 =5.471,P=0.019).The incidence of extraintestinal manifestations in UC patients in the active phase was higher than that of UC patients in the inactive phase (52.9%,92/174 vs.19.8%,17/86),and the difference was statistically significant (x2 =25.908,P<0.01).Conclusions UC is complicated with a variety of extraintestinal manifestations.The most commonly involved organs are liver and gallbladder,joint and oral cavity.The extraintestinal manifestations are more common in female,Uygur,patients with high BMI,youth,patients with a history of intestinal surgery and UC patients at the active phase.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Digestion Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Digestion Ano de publicação: 2018 Tipo de documento: Artigo