Relationship between gestational glucose, lipid metabolism parameters and fetal distress / 中华流行病学杂志

ABSTRACT

Objective To study the relationship between gestational glucose,lipid metabolism parameters and fetal distress.Methods Retrospectively,82 cases of primipara with fetal distress and 246 cases of primipara without any obstetric complications were analyzed.The latter were treated as control group.All the patients were from the same hospital between January,2014 and January,2016.Factors as fasting plasma-glucose (FPG),triglyceride (TG),total cholesterol (TC),high-density lipoprotein (HDL-C),low-density lipoprotein (LDL-C) parameters during early pregnancy,blood glucose of fasting,1 hour and 2 hours in 75 g oral glucose tolerance test (OGTT),at 24 to 28 weeks of gestation,hemoglobin and blood pressure parameters during ante partum were recorded for all the cases while parameters as glucose and lipid,hemoglobin,blood pressure and cesarean section rate were compared between the 2 groups.Results FPG during early gestation,blood glucose of fasting,1 hour and 2 hours 75 g OGTT during mid gestation,systolic blood pressure and diastolic blood pressure during late gestation in the 'fetal distress' group were significantly higher than that of the control group.Hemoglobin during late gestation in the fetal distress group was lower than that of the control group,with statistically significant difference (P＜0.05).The rate of cesarean section in the fetal distress group was higher than that in the control group (x2=4.489,P=0.034).Conclusions High BMI at pre-pregnancy,high blood glucose during early and mid-gestation,high blood pressure and anemia during late gestation were related to the fetal distress group.Cesarean section rate was high for pregnancy women with fetal distress.