Clinical outcomes of synchronous head and neck and esophageal cancer
Radiation Oncology Journal
;
: 172-178, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-73640
ABSTRACT
PURPOSE:
To investigate clinical outcomes of synchronous head and neck and esophageal cancer (SHNEC). MATERIALS ANDMETHODS:
We retrospectively reviewed 27 SHNEC patients treated with curative intent at a single institution. The treatment modality for individual cases was usually determined on a case by case basis.RESULTS:
The median follow-up duration for the surviving patients was 28.2 months. The most common site of head and neck cancer was hypopharyngeal carcinoma (n = 21, 77.7%). The lower esophagus was the most common location of esophageal carcinoma (n = 16, 59.3%). The 2-year progression-free survival (PFS) and overall survival (OS) rates were 57.5% and 39.6%. Major pattern of failure was locoregional recurrence in the study patients. Esophageal cancer stage, the Eastern Cooperative Oncology Group (ECOG) performance status, and pretreatment weight loss were significant prognostic factors for OS in univariate analysis. Treatment-related death was observed in two patients, and one patient developed a grade 4 late treatment-related complication.CONCLUSION:
Although the survival outcome for SHNEC is poor, long-term survival might be achievable with aggressive treatment with stage I-II esophageal cancer and good performance.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Recidiva
/
Neoplasias Esofágicas
/
Redução de Peso
/
Estudos Retrospectivos
/
Seguimentos
/
Intervalo Livre de Doença
/
Esôfago
/
Cabeça
/
Neoplasias de Cabeça e Pescoço
/
Pescoço
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Radiation Oncology Journal
Ano de publicação:
2015
Tipo de documento:
Artigo
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