Acute Pancreatitis Following Organophosphate Intoxication: Analysis of 6 Cases

ABSTRACT

Acute pancreatitis as a complication of organophosphate intoxication has been infrequently addressed. Previous reports have suggested that acute pancreatitis may follow the oral ingestion of several organophosphates. The pathogenesis of this pancreatic damage has been studied in a few animal studies. However, the association between acute pancreatits and human organophosphate intoxication may still not be widely recognized. We experienced 6 cases described as hyperamylasemia and hyperlipasemia with a presumptive diagnosis of acute pancreatitis following organophosphate intoxication, and we analyzed them to provide human baseline data for further studies and patient management. We report these case series with an analysis and a literature review.