Influencing factors of type 2 diabetes mellitus in Chinese: a Meta-analysis / 中华流行病学杂志

ABSTRACT

Objective To evaluate the influencing factors of type 2 diabetes mellitus in Chinese,and provide evidence for developing health promotion policy in the future.Methods Relevant studies published from January 1997 to May 2015 were retrieved from PubMed,Medline,EBSCO,Science Direct,CBM,CNKI,VIP,and Wanfang Database.Quality evaluation of the included literatures was conducted according to the inclusion and exclusion criteria,followed by data extraction and Meta-analysis with software RevMan 4.4.2.Results A total of 29 studies involving 92 970 subjects (11 150 cases and 81 820 controls) were included.The pooled OR and its 95％CI of each influencing factor wereoverweight OR=1.66 (1.49-1.85),abdominal obesity OR=1.98 (1.31-3.01),family history of diabetes OR=3.13 (2.52-3.87),smoking OR=1.46 (1.24-1.72),drinking OR=1.19 (1.09-1.29),hypertension OR =2.64 (2.23-3.13),systolic blood pressure (SBP) OR =1.15(1.06-1.24),hyperlipoidemia OR=2.26 (1.75-2.92),total cholesterol (TC) OR=1.87 (1.14-3.08),triglyceride (TG) OR=1.73 (1.23-2.44),history of coronary heart disease (CHD) OR=2.55 (1.78-3.65),cerebrovascular accident (CVA) OR=2.21 (1.62-3.02),dietary fat OR=0.52 (0.27-0.99).The results of subgroup analysis identified 4 common influencing factors shared by the three subgroups,i.e.overweight,family history of diabetes,smoking and hypertension.Conclusion Overweight,abdominal obesity,family history of diabetes,smoking,drinking,hypertension,SBP,TC,TG,history of CHD,history of CVA,and subtypes of dietary fat are the influencing factors for type 2 diabetes mellitus in Chinese.Among these factors,overweight in recent 20 years,family history of diabetes,smoking and hypertension are persistent factors.More attention should be paid to overweight and obesity.