Diagnostic and epidemiological features of the first two HIV-2 indigenous infections in Hunan province / 中华流行病学杂志
Chinese Journal of Epidemiology
; (12): 1077-1081, 2018.
Article
em Zh
| WPRIM
| ID: wpr-738100
Biblioteca responsável:
WPRO
ABSTRACT
Objective: To study the diagnostic and epidemiological features of the first two HIV-2 indigenous cases in Hunan province. Methods: Blood samples from two individuals with "HIV antibody indeterminate" and HIV-2 specific band showed by HIV-1/2 western blotting method, were repeatedly collected and detected under HIV 1+2 strip immunoassay and PCR, in Changsha city, Hunan province, through March to November, 2017. An epidemiological survey was carried out at the same time. Results: Our findings showed that the two cases were sex partners, without histories of sexual contact with foreigners and the source of infection was unknown. Results from the HIV 1+2 antibody confirmation test showed that they were "HIV-2 antibody positive" . Through amplifying and sequencing the gag area of HIV-2 and BLAST, the similarity of HIV-2 strains presented as 98%. The results also showed that there were HIV-2 specific fragments in the two cases. Conclusion: HIV-2 indigenous cases had never been reported in China. These cases had brought new challenge on prevention, diagnosis and treatment of HIV/AIDS in China.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Comportamento Sexual
/
Parceiros Sexuais
/
Anticorpos Anti-HIV
/
Infecções por HIV
/
China
/
Western Blotting
/
Inquéritos e Questionários
/
HIV-2
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Epidemiology
Ano de publicação:
2018
Tipo de documento:
Article