Poorly Differentiated Neuroendocrine Carcinoma of the Eyelid
Journal of the Korean Ophthalmological Society
;
: 861-866, 2018.
Artigo
em Coreano
| WPRIM
| ID: wpr-738580
ABSTRACT
PURPOSE:
To report a case of poorly differentiated neuroendocrine carcinoma of the eyelid. CASESUMMARY:
A 70-year-old male presented with a 5-month history of a right upper eyelid mass. The mass appeared as 1.2 × 1.2 cm on the right upper eyelid. A mass excision was performed under frozen section control. The tumor was completely excised with a safety margin clearance and an upper eyelid reconstruction was performed. Histopathological examination revealed a tumor composed of small atypical cells which showed a high nuclear/cytoplasm ratio, nuclear molding, and increased mitotic activity. Immunohistochemical examination revealed positive reactivity for Ki-67, synaptophysin, CD56, and negative reactivity for chromogranin, cytokeratin 20, and thyroid transcription factor-1.CONCLUSIONS:
Primary neuroendocrine carcinoma of the eyelid is extremely rare, but the tumor has high malignancy and readily metastasizes. Poorly differentiated neuroendocrine carcinoma should be considered in the differential diagnosis of a rapidly growing eyelid mass.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Glândula Tireoide
/
Carcinoma de Célula de Merkel
/
Sinaptofisina
/
Carcinoma de Células Pequenas
/
Carcinoma Neuroendócrino
/
Diagnóstico Diferencial
/
Queratina-20
/
Pálpebras
/
Secções Congeladas
/
Fungos
Tipo de estudo:
Estudo diagnóstico
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2018
Tipo de documento:
Artigo
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