Transjugular intrahepatic portosystemic shunt creation for portal hypertension in patients with hepatocellular carcinoma: A systematic review
Gastrointestinal Intervention
;
: 167-171, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-739174
ABSTRACT
BACKGROUND:
To evaluate the safety and efficacy of transjugular intrahepatic portosystemic shunt (TIPS) creation for the management of portal hypertension in patients with hepatocellular carcinoma (HCC).METHODS:
A literature search of the MEDLINE/PubMed and Embase databases was conducted. All articles reporting the outcomes of TIPS creation for variceal bleeding and refractory ascites and hepatic hydrothorax in patients with HCC were included. Exclusion criteria were non-English language, sample size < 5, data not extractable, and data reported in another article.RESULTS:
A total of 280 patients (mean age, 48–58; male gender, 66%) from five articles were included. TIPS creation was performed for variceal bleeding in 79% and refractory ascites and/or hepatic hydrothorax in 26% of patients. Technical and clinical success was achieved in 99% and 64% of patients, respectively. Clinical failure occurred in 36% of patients due to rebleeding or recurrent bleeding (n = 77) or no resolution or improvement of refractory ascites and hepatic hydrothorax (n = 24). One percent of patient had major complications, including accelerated liver failure (n = 1) and multi-organ failure resulting from hemorrhagic shock (n = 1), all of which resulted in early (i.e., within 30 days) death. Hepatic encephalopathy occurred in 40% of patients after TIPS creation. Lung metastasis was found 1% of patient 5 months (n = 1) and 72 months (n = 1) after TIPS creation.CONCLUSION:
TIPS creation seems to be safe and effective for the management of portal hypertension in patients with HCC.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ascite
/
Choque Hemorrágico
/
Derivação Portossistêmica Cirúrgica
/
Varizes Esofágicas e Gástricas
/
Encefalopatia Hepática
/
Falência Hepática
/
Carcinoma Hepatocelular
/
Tamanho da Amostra
/
Derivação Portossistêmica Transjugular Intra-Hepática
/
Hemorragia
Tipo de estudo:
Revisões Sistemáticas Avaliadas
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Gastrointestinal Intervention
Ano de publicação:
2018
Tipo de documento:
Artigo
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