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Polydipsia as a Precursor of Manic Episode in Bipolar Affective Disorder Patients with Alcohol Use Disorder
Clinical Psychopharmacology and Neuroscience ; : 114-117, 2018.
Artigo em Inglês | WPRIM | ID: wpr-739453
ABSTRACT
Bipolar affective disorder (BD) diagnosis and initiation of appropriate treatment are often delayed, and this is associated with poorer outcomes, such as rapid cycling or cognitive decline. Therefore, identifying certain warning signs of a probable successive episode during the inter-episode phase is important for early intervention. We present the retrospective data of three cases of BD. Our first case had a history of alcohol use disorder (AUD), where he drank in a dipsomaniac manner, and the other two cases had dipsomaniac alcohol use before their manic attacks, and none of them had any AUD after the mood episode was over. Two brothers also had hypertensive episodes during the manic attacks. None of the cases reported increased fluid intake when they were euthymic. We suggest that polydipsia in BD may be a warning sign of an upcoming manic episode, especially in those patients with AUD. Polydipsia in BD may be caused or facilitated by a combination of hyperdopaminergic activity, hypothalamic dysfunction, and dysregulated renin-angiotensin system. To be able to prevent new episodes, a patient’s drinking habits and change in fluid intake should be asked at every visit. Those patients with a history of alcohol abuse should especially be informed about polydipsia and manic episode association.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Sistema Renina-Angiotensina / Transtorno Bipolar / Comorbidade / Estudos Retrospectivos / Intervenção Educacional Precoce / Transtornos do Humor / Irmãos / Diagnóstico / Ingestão de Líquidos / Alcoolismo Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico Limite: Humanos Idioma: Inglês Revista: Clinical Psychopharmacology and Neuroscience Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Sistema Renina-Angiotensina / Transtorno Bipolar / Comorbidade / Estudos Retrospectivos / Intervenção Educacional Precoce / Transtornos do Humor / Irmãos / Diagnóstico / Ingestão de Líquidos / Alcoolismo Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico Limite: Humanos Idioma: Inglês Revista: Clinical Psychopharmacology and Neuroscience Ano de publicação: 2018 Tipo de documento: Artigo