Bronchiolitis severity according to the infected viruses
Allergy, Asthma & Respiratory Disease
;
: 47-53, 2018.
Artigo
em Coreano
| WPRIM
| ID: wpr-739504
ABSTRACT
PURPOSE:
The aim of this study was to evaluate the severity of disease in children with acute bronchiolitis according to the type of infected virus.METHODS:
From November 2007 to May 2015, 768 patients under 2 years of age who underwent real time-polymerase chain reaction of nasopharyngeal aspirates admitted to the Department of Pediatrics of Dongguk University Ilsan Hospital for acute bronchiolitis were enrolled. Severe bronchiolitis was defined as presence of one or more kinds among tachypnea, chest retraction, needs of O2 inhalation or ventilator care.RESULTS:
The severity of bronchiolitis was increased with shorter fever duration (P < 0.001) and previous wheezing episodes (P = 0.005). In the case of single infection, respiratory syncytial virus (RSV) A only increased the severity of acute bronchiolitis (P = 0.012). However, the severity of illness decreased when RSV A coinfected with adenovirus (P = 0.034), human rhinovirus (P = 0.038), or human coronavirus NL63 (P = 0.042). On the other hand, when human rhinovirus was coinfected with enterovirus (P = 0.013) or parainfluenza 3 (P = 0.019), the severity was increased. When human metapneumovirus coinfected with human bocavirus, the severity was increased (P = 0.038).CONCLUSION:
Acute bronchiolitis was associated with increased severity only when RSV A infected solely, but several viruses increased or decreased the severity when coinfection occurred. Therefore, it may be helpful in predicting the course of the acute bronchiolitis according to the affected virus.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pediatria
/
Vírus Sinciciais Respiratórios
/
Rhinovirus
/
Tórax
/
Bronquiolite
/
Ventiladores Mecânicos
/
Adenoviridae
/
Sons Respiratórios
/
Inalação
/
Infecções por Paramyxoviridae
Limite:
Criança
/
Humanos
/
Lactente
Idioma:
Coreano
Revista:
Allergy, Asthma & Respiratory Disease
Ano de publicação:
2018
Tipo de documento:
Artigo
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