Potential Implications of Long Noncoding RNAs in Autoimmune Diseases
Immune Network
;
: e4-2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-740210
ABSTRACT
Long noncoding RNAs (lncRNAs) are non-protein coding RNAs of more than 200 nucleotides in length. Despite the term “noncoding”, lncRNAs have been reported to be involved in gene expression. Accumulating evidence suggests that lncRNAs play crucial roles in the regulation of immune system and the development of autoimmunity. lncRNAs are expressed in various immune cells including T lymphocytes, B lymphocytes, macrophages, neutrophils, dendritic cells, and NK cells, and are also involved in the differentiation and activation of these immune cells. Here, we review recent studies on the role of lncRNAs in immune regulation and the differential expression of lncRNAs in various autoimmune diseases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Doenças Autoimunes
/
Células Dendríticas
/
RNA
/
Linfócitos B
/
Células Matadoras Naturais
/
Linfócitos T
/
Autoimunidade
/
Expressão Gênica
/
Codificação Clínica
/
RNA Longo não Codificante
Idioma:
Inglês
Revista:
Immune Network
Ano de publicação:
2019
Tipo de documento:
Artigo
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