TFE3-Expressing Perivascular Epithelioid Cell Tumor of the Breast
Journal of Pathology and Translational Medicine
;
: 62-65, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-741207
ABSTRACT
Perivascular epithelioid cell tumor (PEComa) is a very rare mesenchymal tumor with a distinctive morphology and immunophenotype. PEComas usually harbor TSC2 alterations, although TFE3 translocations, which occur in MiT family translocation renal cell carcinoma and alveolar soft part sarcoma, are also possible. We recently experienced a case of PEComa with TFE3 expression arising in the breast. An 18-year-old female patient presented with a right breast mass. Histologically, the tumor consisted of epithelioid cells with alveolar structure and showed a diffuse strong expression of HMB45 and TFE3. TSC2 was preserved. Melan A and smooth muscle actin were negative. To our knowledge, this is the first Korean case of PEComa of the breast that intriguingly presented with TFE3 expression.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Mama
/
Carcinoma de Células Renais
/
Células Epitelioides
/
Actinas
/
Sarcoma Alveolar de Partes Moles
/
Neoplasias de Células Epitelioides Perivasculares
/
Antígeno MART-1
/
Músculo Liso
Limite:
Adolescente
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Pathology and Translational Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
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