Clinical Implication of Surgically treated Abdominoperineal Soild Tumor in the Newborn : A Single-Center Experience
Neonatal Medicine
; : 23-28, 2018.
Article
em Ko
| WPRIM
| ID: wpr-741657
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: Abdominoperineal solid tumors presenting in neonates often require surgical intervention during the neonatal period. Although we report our single-center experience, this study would be meaningful to understand the clinical implications of these neoplasms. METHODS: We retrospectively reviewed and analyzed the clinical data and characteristics of 22 patients (≤28 days old) diagnosed with histopathologically confirmed abdominoperineal solid neoplasms (benign or malignant) after surgical resection. RESULTS: The mean gestational age and postnatal age at the time of operation were 38.3±1.8 weeks and 13.5±8.3 days, respectively. Most patients (18/22, 81.8%) were diagnosed during antenatal care visits; however, 4 (18.2%) were identified after birth. The mean tumor size was 6.4×5.3 cm (3.5–17.0 cm), and tumors occurred most frequently within the sacrococcygeal region (8/22, 36.4%). Histopathologically, 14 patients (63.6%) demonstrated benign tumors and 8 (36.4%) demonstrated malignant tumors. Germ cell tumors and hepatoblastomas were the most commonly observed tumors. Fortunately, all patients showed a localized pattern of tumor involvement without distant metastasis. No recurrence or mortality was observed during the follow-up period (mean 66.4±44.2 months). CONCLUSION: Abdominoperineal solid tumors occurring in neonates show variable clinical patterns during the antenatal and postnatal monitoring/screening periods. We conclude that aggressive and multidisciplinary approaches could achieve good clinical results in these patients.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Recidiva
/
Região Sacrococcígea
/
Estudos Retrospectivos
/
Seguimentos
/
Mortalidade
/
Idade Gestacional
/
Hepatoblastoma
/
Neoplasias Embrionárias de Células Germinativas
/
Parto
/
Metástase Neoplásica
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
/
Newborn
Idioma:
Ko
Revista:
Neonatal Medicine
Ano de publicação:
2018
Tipo de documento:
Article