Expression and significance of serum INHB, IGF-1, VEGF and E2 in patients with polycystic ovary syndrome / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 181-183,187, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-742882
ABSTRACT
Objective To study the expression and significance of serum inhibin B (INHB), insulin-like growth factor-1 (IGF-1), vascular endothelial growth factor (VEGF) and estradiol (E2) in patients with polycystic ovary syndrome (PCOS).Methods A total of 45patients with PCOS in the hospital from April 2015to May 2016, were selected as observation group.In addition, 45healthy women who underwent physical examination due to male infertility were selected as control group.The significance and diagnostic value of serum INHB, IGF-1, VEGF and E2in PCOS were analyzed.Results The levels of serum INHB, IGF-1, VEGF and E2in observation group were significantly higher than those of control group (P<0.05).The receiver operating characteristic curve (ROC curve) analysis showed that the AUC of INHB, IGF-1, VEGF and E2were 0.935, 0.988, 0.992and 0.759, respectively.The sensitivity of PCOS were 80.93%, 81.18%, 79.12%and79.07%, while the specificity of PCOS were 73.05%, 75.17%, 77.49%and 78.59%, respectively.ConclusionSerum INHB, IGF-1, VEGF and E2are highly expressed in patients with PCOS, which can be used as an important indicators in the diagnosis of PCOS.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
International Journal of Laboratory Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
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