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Congenital heart disease and neurodevelopment in children from the perspective of genetics / 中华实用儿科临床杂志
Article em Zh | WPRIM | ID: wpr-743526
Biblioteca responsável: WPRO
ABSTRACT
Children with congenital heart disease (CHD) are at risk of neurodevelopmental disorder (NDD) which can be manifested as a diversity of clinical type.Up to 20%-30% of CHD children have genetic abnormalities.As an independent risk factor for NDD,genetic abnormalities may predict a poorer neurodevelopmental outcome in these children.Because neurodevelopmental outcomes are closely related to the presence of underlying syndromes or genetic abnormalities,early diagnosis is the key to establish the prognosis of it,which is conducive to provide guidance for the children and their families in early time.In order to draw the attention of pediatric clinicians and CHD families and provide more comprehensive support for those children,this brief review is written for illustrate the relationship between CHD children and their neurodevelopmental outcome from the perspective of genetics.
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Texto completo: 1 Índice: WPRIM Tipo de estudo: Guideline / Prognostic_studies / Screening_studies Idioma: Zh Revista: Chinese Journal of Applied Clinical Pediatrics Ano de publicação: 2019 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Tipo de estudo: Guideline / Prognostic_studies / Screening_studies Idioma: Zh Revista: Chinese Journal of Applied Clinical Pediatrics Ano de publicação: 2019 Tipo de documento: Article