Cytogenetic analysis on 5329 children in genetic counseling / 实用医学杂志
The Journal of Practical Medicine
;
(24): 479-482, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-743759
ABSTRACT
Objective To explore the relationship between chromosomal abnormalities and diseases in children by analyzing chromosome karyotypes. Methods The chromosome karyotype analysis of peripheral lymphocytes in 5 329 children was performed. Results In all, abnormal karyotype were found in 1 723 cases (32.33%) , in which the numerical chromosome abnormalities were detected in 1 539 (89.32%) , following by 125 cases of structural chromosome abnormalities (7.25%) , 53 cases of sex reverse syndrome (3.08%) , and 6 cases of true hermaphroditism (0.35%). The chromosome polymorphism were detected in 228 cases (4.28%). Conclusions The numerical chromosome abnormalities is most frequent chromosomal aberration and is one of the important causes that result in mental retardation, growth delay and disorders of sex development in children.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
The Journal of Practical Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS