Prospects and application of curvilinear distraction osteogenesis / 中国组织工程研究

ABSTRACT

BACKGROUND: Insufficient development of craniofacial bone and jaw defects are common problems in clinical practice of maxillofacial surgery. How to repair is always a problem. Because distraction osteogenesis has the advantages of small trauma, avoiding bone grafting, and prolonging the synchronization of surrounding soft tissue, it holds critical role in increasing alveolar bone mass, prolonging jaw bone, repairing bone defect, and closing bone gap. OBJECTIVE: To summarize and discuss the technical methods, application, limitations and development trends of various curved distractors. METHODS: Relevant articles published from January 2000 to October 2018 were retrieved from CNKI, WanFang, PubMed and Embase databases and National Intellectual Property Office Patent Search and Analysis Platform. The key words were "distraction osteogenesis, curvilinear distraction, curved distractor, reconstruction, research progress, mandibular, maxilla, defect, customized distractor, finite element method" in Chinese and English, respectively. Fifty-eight eligible articles were included for review. RESULTS AND CONCLUSION: (1) The early distraction osteogenesis devices are mostly external unidirectional distractors. With the development of various technologies, various intra-oral distractors, such as spiral distractor, curve distractor, bidirectional distractor, three-focus distractor and automatic distractor. (2) In view of the special anatomical shape of the jaw, there are many arc-faced structures. In order to make the new bone closer to the contour shape of the jaw, curved distraction osteogenesis has gradually become a research hotspot. (3) Although the existing curved distractors provide a reliable technical means for jaw defects, they still have a certain degree of limitation. Due to the existence of problems such as traction and force, the true meaning curve and even the three-dimensional distraction are not completed. The development of individualized stretchers combined with relevant innovations, and towards miniaturization and stabilization development is still the mainstream trend of future research on curvilinear distraction.