Methodology of drug screening and target identification for new necroptosis inhibitors / 药物分析学报
Journal of Pharmaceutical Analysis
;
(6): 71-76, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-744110
ABSTRACT
Apoptosis has been considered as the only form of regulated cell death for a long time. However, a novel form of programmed cell death called necroptosis was recently reported. The process of necroptosis is regulated and plays a critical role in the occurrence and development of multiple human diseases. Thus, the study on the molecular mechanism of necroptosis and its effective inhibitors has been an attractive field for researchers. Herein, we introduce the molecular mechanism of necroptosis and focus on the literature about necroptosis drug screening in recent years. In addition, the identification of the critical drug targets of the necroptosis is also discussed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Idioma:
Chinês
Revista:
Journal of Pharmaceutical Analysis
Ano de publicação:
2019
Tipo de documento:
Artigo
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