Two Cases of Wernicke's Encephalopathy That Developed during Total Parenteral Nutrition in Colon Cancer Patients Treated with 5-Fluorouracil-based Chemotherapy / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 158-163, 2014.
Artigo
em Coreano
| WPRIM
| ID: wpr-74442
ABSTRACT
Wernicke's encephalopathy (WE) caused by thiamine deficiency is an acute neurological disorder. Clinically, the classic triad of WE consists of ophthalmoplegia, ataxia, and mental status changes. Thiamine deficiency is known to occur commonly in chronic alcoholic patients. Sometimes, it can occur in patients after gastrointestinal surgery and in those with malabsorption. In addition, patients undergoing renal dialysis, suffering from hyperemesis gravidarum, receiving total parenteral nutrition (TPN), and being treated with chemotherapeutic agents are also prone to develop thiamine deficiency. Herein, we report two cases of WE that developed following simultaneous 5-fluorouracil (5-FU) chemotherapy and TPN in colon cancer patients which was successfully treated with thiamine administration.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tiamina
/
Complexo Vitamínico B
/
Encefalopatia de Wernicke
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Nutrição Parenteral Total
/
Neoplasias do Colo
/
Fluoruracila
/
Antimetabólitos Antineoplásicos
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Gastroenterology
Ano de publicação:
2014
Tipo de documento:
Artigo
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