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The research progress of Alzheimer's disease based on gray matter volume and cerebral blood flow / 中华行为医学与脑科学杂志
Chinese Journal of Behavioral Medicine and Brain Science ; (12): 91-94, 2019.
Artigo em Chinês | WPRIM | ID: wpr-744752
ABSTRACT
In recent years,magnetic resonance imaging (MRI) has been widely used in the early diagnosis as well as long-term follow-up study of Alzheimer's disease (AD).The studies were reviewed which applied the structural MRI and arterial spin labeling MRI (ASL-MRI) in AD over the past 20 years,and found more gray matter volume loss in multiple brain structures in individuals with AD spectrum.Among them,medial temporal lobe atrophy and posterior cortical atrophy are the most diagnostic.Meanwhile,cerebral blood flow changes in various brain regions with the progression of the AD.More investigations combining the changes of gray matter volume and cerebral blood flow to explore pathophysiological mechanisms underlying cognitive decline in AD spectrum are necessary in the future.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo observacional / Estudo prognóstico / Estudo de rastreamento Idioma: Chinês Revista: Chinese Journal of Behavioral Medicine and Brain Science Ano de publicação: 2019 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo observacional / Estudo prognóstico / Estudo de rastreamento Idioma: Chinês Revista: Chinese Journal of Behavioral Medicine and Brain Science Ano de publicação: 2019 Tipo de documento: Artigo