Application of vincristine-loaded platelet therapy in three dogs with refractory immune-mediated thrombocytopenia
Journal of Veterinary Science
;
: 127-130, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-74485
ABSTRACT
Three dogs presented with refractory immune-mediated thrombocytopenia (IMT). All patients failed to respond to prednisone, which is considered a mainstay of immunosuppressive therapy. Vincristine-loaded platelets (VLPs), which act selectively on mononuclear phagocytes,were introduced. After the VLPs were transfused, two dogs responded quickly withimproved clinical signs while the third dogwith recurrent IMT was euthanized due to its deteriorating condition. This case report describesthe efficacy of VLP therapy in refractory IMT patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vincristina
/
Púrpura Trombocitopênica Idiopática
/
Transfusão de Plaquetas
/
Doenças do Cão
/
Antineoplásicos Fitogênicos
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2015
Tipo de documento:
Artigo
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