Contrast-enhanced ultrasound quantitative analysis in diagnosis of prostate lesions / 中国医师杂志

ABSTRACT

Objective To investigate the diagnosis value of contrast-enhanced transrectal ultrasound (CETRUS) quantitative analysis in different types of prostate lesions.Methods 104 patients suspected prostate cancer from the Second Xiangya Hospital of Central South University from Januray 2013 to March 2015 were selected to undergo biopsy.All patients underwent preoperative CETRUS before biopsy.Quantitative analysis of focal prostate was performed with QLAB software.Contrast parameters of each region of interest were recorded and the differences between parameters were compared.Results The contrast parameters of rise time (RT),peak intensity (PI),mean transit time (MTT),area under the curve (AUC),time from peak to one half (TPH),wash in slope (WiS) and time to peak (TTP) of 26 malignant nodules were significantly different from those of the contralateral isotropic glands at the same depth (P ＜ 0.05).There was no significant difference in the above parameters between 33 benign nodules and the contralateral glands of the same depth (P ＞ 0.05).There were significant difference in the above parameters except MTT between the internal gland and the external gland in 18 cases of diffuse prostatic hyperplasia (P ＜0.05).There was no significant difference in the above parameters between the internal gland and the external gland in 28 cases of diffuse prostate cancer.In addition,there was significant difference in Gleason score between diffuse and nodular prostate cancer (P ＜ 0.05).Conclusions Quantitative analysis of CETRUS is expected to be an effective method for differentiating benign and malignant prostatic lesions.