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NF-κB signaling pathway in psoriasis / 中华皮肤科杂志
Chinese Journal of Dermatology ; (12): 361-363, 2019.
Article em Zh | WPRIM | ID: wpr-745799
Biblioteca responsável: WPRO
ABSTRACT
Nuclear factor (NF)-κB,a kind of protein transcription factor,mediates inflammation and other complex biological processes,and is a key regulator of many immune and inflammatory pathways,cell proliferation,differentiation and apoptosis.Psoriasis is an inflammatory skin disease characterized by increased levels of phosphorylated NF-κB,which leads to an increase in anti-apoptotic activity of keratinocytes and aggravation of inflammatory reactions.This review summarizes advances in NF-κB signaling pathway and its role in psoriasis.
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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Journal of Dermatology Ano de publicação: 2019 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Journal of Dermatology Ano de publicação: 2019 Tipo de documento: Article