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Fatigue and related factors after liver transplantation
Korean Journal of Hepato-Biliary-Pancreatic Surgery ; : 149-153, 2015.
Artigo em Inglês | WPRIM | ID: wpr-74621
ABSTRACT
BACKGROUNDS/

AIMS:

Fatigue is common in chronic hepatitis and end-stage liver disease. However, little is known about fatigue after liver transplantation (LT). We therefore evaluated the prevalence, severity, and related factors of fatigue after LT.

METHODS:

We retrospectively reviewed adult recipients who responded to our survey at outpatient clinics between April and May 2013. Fatigue and its severity were assessed using a questionnaire with the Fatigue Severity Scale (FSS). We defined fatigue as FSS of 4.0 or more and severe fatigue as FSS of 5.1 or more. The related factors including hepatocellular carcinoma and complications were analyzed.

RESULTS:

A total of 93 patients were included in this study. The mean age was 54.9 (19-76) years and two-thirds were men (67.7%). Living donor LT was 77.4%. Hepatitis B related liver disease was the main underlying disease (77.4%), with hepatocellular carcinoma accompanied in 33.3%. The mean follow-up period was 66.8+/-43.2 (2-171) months. The mean FFS was 2.83+/-1.48 (1.0-6.7) overall and 5.10+/-0.82 (4.0-6.7) in the fatigue group. Of the 93 adult patients, fatigue was presented in 20 patients (21.5%). Among these, 9 patients (45.0%) showed severe fatigue. Even though post-LT complications tended to be greater in the fatigue group (50.0% vs. 30.1% in the non-fatigue group, p=0.098), there were no significant related factors of fatigue after LT, including hepatocellular carcinoma and major complication.

CONCLUSIONS:

Fatigue is present in a considerable portion of recipients after LT, and almost half of them have severe fatigue. Further efforts are needed to decrease fatigue in LT recipients.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prevalência / Estudos Retrospectivos / Fatores de Risco / Seguimentos / Transplante de Fígado / Carcinoma Hepatocelular / Doadores Vivos / Fadiga / Instituições de Assistência Ambulatorial / Hepatite B Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo de prevalência / Estudo prognóstico / Fatores de risco Limite: Adulto / Humanos / Masculino Idioma: Inglês Revista: Korean Journal of Hepato-Biliary-Pancreatic Surgery Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prevalência / Estudos Retrospectivos / Fatores de Risco / Seguimentos / Transplante de Fígado / Carcinoma Hepatocelular / Doadores Vivos / Fadiga / Instituições de Assistência Ambulatorial / Hepatite B Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo de prevalência / Estudo prognóstico / Fatores de risco Limite: Adulto / Humanos / Masculino Idioma: Inglês Revista: Korean Journal of Hepato-Biliary-Pancreatic Surgery Ano de publicação: 2015 Tipo de documento: Artigo