Expression of toll-like receptors signaling pathway in chronic rhinosinusitis with nasal polyps / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 1059-1062, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-746674
ABSTRACT
OBJECTIVE@#To investigate the expression of Toll-like receptors (TLRs) signaling pathway in chronic rhinosinusitis (CRS) with nasal polyps.@*METHOD@#Gene microarray analysis was used to detect the expression of TLRs signaling pathway in CRS with nasal polyps.@*RESULT@#Of 19 differentially expressed (two fold changes), 4 genes were upregulated and 15 genes were downregulated.@*CONCLUSION@#The differentially expressed genes in TLRs signaling pathway may exert its effect in the pathogenesis of CRS. In addition, the roles of TLR9 and its agonists need further study.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sinusite
/
RNA Mensageiro
/
Transdução de Sinais
/
Estudos de Casos e Controles
/
Pólipos Nasais
/
Doença Crônica
/
Análise de Sequência com Séries de Oligonucleotídeos
/
Receptores Toll-Like
/
Genética
/
Metabolismo
Tipo de estudo:
Estudo observacional
Limite:
Adolescente
/
Adulto
/
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Ano de publicação:
2009
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS