Surgery added with fluconazole in treatment of fungal rhinosinusitis / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To explore the effect of surgery added with antifungal agents in treatment of fungal rhinosinusitis.@*METHOD@#One hundred and two consecutive patients with fungal rhinosinusitis were randomly divided into two groups the control group (n=48) were treated with surgery alone, the treatment group (n=54) were treated with surgery plus antifungal therapy during operation and postoperation. The patients were followed up for 6 months and the relapse rates between two groups were compared.@*RESULT@#No relapse was observed in the treatment group. The relapse rate of the control group was 20.8% (P < 0.01).@*CONCLUSION@#Surgery plus antifungal therapy can prevent the relapse of fungal rhinosinusitis significantly.