Study of protective effects on noise-induced hearing loss using N-acetyl-cysteine / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 1040-1041, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-748023
ABSTRACT
OBJECTIVE@#To evaluate the protective effects of oral administration of N-acetyl-cysteine (NAC) on noise-induced hearing loss.@*METHOD@#Three hundred sixty three volunteers were recruited and randomly divided into two groups experimental group (n=223) and control group (n=140). The subjects had received oral administration of NAC in the experimental group and placebo in the control group before noise exposure. The routine audiometric evaluation and ABR testing were performed and recorded pre- and post-noise exposure. The statistical analysis was carried out on the data obtained from two groups with SPSS 11.0.@*RESULT@#The hearings of all the participatory were changed after noise exposure, but there were statistically significant differences between two groups.@*CONCLUSION@#The protective effects of NAC were prominent on the noise-induced hearing loss.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Acetilcisteína
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Perda Auditiva Provocada por Ruído
/
Militares
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Ano de publicação:
2011
Tipo de documento:
Artigo
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