Characteristics of intrinsic laryngeal muscle after recurrent laryngeal nerve injury / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To investigate the electrophysiological characteristics and pathological changes in different recurrent laryngeal nerve injury models.@*METHOD@#Twenty dogs were divided into different models of recurrent laryngeal nerve injury. Electrophysiological changes of animal models and histopathological changes in laryngeal muscles were investigated at different time.@*RESULT@#Amplitude of MUP in TA decreased at first and then increased a little, while duration of MUP keeps decreased. The latent periods of the evoked potential in the incomplete injury group increased at first and then went down. In animal histopathological investigation, the lighter of the muscle injuries and the bigger of the diameter of muscle fibers and fascicles, and the smaller of the number of cellular nucleolus per square inch. In the early periods after injury, the correlation among the standard amplitude, threshold amplitude, maximum amplitude of EP and the diameter of fascicles were positive; while in the late period, the correlation among the amplitude, duration, area of MUP and nucleolus number was positive.@*CONCLUSION@#The physiological characteristics of laryngeal nerves and muscles could be known. LEMG was an important method in diagnosis of laryngeal nerve and muscle diseases.