A Case of Pure Red Cell Aplasia Associated with Angioimmunoblastic T-cell Lymphoma / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 115-117, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-74857
ABSTRACT
Pure red cell aplasia is a bone marrow failure characterized by a progressive normocytic anemia and reticulocytopenia without leucopenia and thrombocytopenia. It is associated with various hematologic diseases. However, pure red cell aplasia with angioimmunoblastic T cell lymphoma has rarely been reported. Here we describe a 43-year-old woman with pure red cell aplasia associated with angioimmunoblastic T-cell lymphoma. She had severe anemia (hemoglobin 6.9 g/dL) and a low reticulocyte count (0.2%). Direct and indirect Coombs' tests were positive. A CT scan of the abdomen revealed marked hepatosplenomegaly and small multiple lymphadenopathies. A bone marrow biopsy revealed focal infiltration of abnormal lymphoid cells and absence of red cell precursors. Splenic biopsy was compatible with angioimmunoblastic T-cell lymphoma. Ultimately, diagnosis of pure red cell aplasia associated with angioimmunoblastic T-cell lymphoma was made. After initiating CHOP therapy, the patient achieved complete remission, which was accompanied, shortly thereafter, by a rise in hemoglobin levels which finally returned to normal.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Trombocitopenia
/
Biópsia
/
Medula Óssea
/
Hemoglobinas
/
Teste de Coombs
/
Linfócitos
/
Linfócitos T
/
Linfoma de Células T
/
Aplasia Pura de Série Vermelha
/
Contagem de Reticulócitos
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Cancer Research and Treatment
Ano de publicação:
2010
Tipo de documento:
Artigo
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