Expression of cancer-testis antigen SCP-1 mRNA in human nasopharyngeal carcinoma / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 343-345, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-748823
ABSTRACT
OBJECTIVE@#To investigate the gene expression of Cancer-Testis Antigen SCP-1 in human nasopharyngeal carcinoma.@*METHOD@#The SCP-1 mRNA were examined in the tumor tissues of 28 nasopharyngeal carcinoma cases and control pharynx vasitis tissues of 40 non-cancer cases by reverse transcriptase polymerase chain reaction. A randomized sample of positive expression of SCP-1 mRNA was extracted for DNA sequencing to examine the reliability of results. The correlation of the expression of SCP-1 mRNA with clinical data was analyzed by statistical method.@*RESULT@#The expression frequency of SCP-1 mRNA was 14.3% (4/28) in nasopharyngeal carcinoma and zero (0/40) in control pharynx vasitis tissue of non-cancer cases (P 0.05).@*CONCLUSION@#SCP-1 mRNA is expressed in some nasopharyngeal carcinoma, suggesting that SCP-1 might be a new tumor target antigen of nasopharyngeal carcinoma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
RNA Mensageiro
/
Carcinoma de Células Escamosas
/
Estudos de Casos e Controles
/
Neoplasias Nasofaríngeas
/
Alergia e Imunologia
/
Genética
/
Metabolismo
/
Antígenos de Neoplasias
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Ano de publicação:
2007
Tipo de documento:
Artigo
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