The curative effect of corticosteroid on acute otitis media with middle ear effusion / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To investigate the curative effect of corticosteroid on acute otitis media (AOM) with middle ear effusion.@*METHOD@#Forty-three children (43 ears) with AOM and abnormal tympanogram were enrolled in a prospective, randomized trial. Twenty-three cases (23 ears) were treated with Dexamethasone and Cefuroxime Sodium, while the other 20 cases (20 ears) were only treated with Cefuroxime Sodium.@*RESULT@#The period of normalization of tympanometric findings in Dexamethasone treatment group was (54.6+/-6.2) days, which was much longer than that in the group without Dexamethasone treatment (38.5+/-6.1). Three months after treatment, the curative rate of Dexamethasone treatment group was higher than that of the group without Dexamethasone treatment.@*CONCLUSION@#Corticosteroid can obviously improve middle ear effusion and shorten the duration of middle ear effusion of AOM in the first 2 weeks. To some extent, corticosteroid can also improve middle ear effusion in long term. It indicates that corticosteroid be used as an effective adjunctive drug in treating AOM with middle ear effusion.