Expression of Livin in laryngeal squamous cell carcinoma and relationship with bFGF / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 114-116, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-749098
ABSTRACT
OBJECTIVE@#To detect the roles of Livin and its relationship with bFGF in laryngeal squamous cell carcinoma (LSCC) through observing the expression of Livin and bFGF in laryngeal squamous cell carcinoma.@*METHOD@#Expression of Livin and bFGF in 41 cases of LSCC (11 cases with lymph node metastasis) and 20 cases of normal soft palate mucosa were detected by immunohistochemistry.@*RESULT@#Livin were positively detected in 29 (70.73%) cases of LSCC and negatively detected in all normal soft palate tissue. The positive rate of Livin was higher in LSCC than that in normal soft palate tissue and the expressions were significantly associated with lymph node metastasis status (P 0.05). The expression of Livin was positively correlated with the expression of bFGF.@*CONCLUSION@#The elevated expression of Livin in LSCC might play an important role in the development of laryngeal squamous cell carcinoma and bFGF might be involved in the process.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Carcinoma de Células Escamosas
/
Neoplasias Laríngeas
/
Fator 2 de Crescimento de Fibroblastos
/
Proteínas Adaptadoras de Transdução de Sinal
/
Proteínas Inibidoras de Apoptose
/
Metabolismo
/
Proteínas de Neoplasias
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Ano de publicação:
2008
Tipo de documento:
Artigo
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