Cerebral small vessel disease and cognitive impairment: the significance of structural and functional connectivity / 国际脑血管病杂志

ABSTRACT

Cerebral small vessel disease (CSVD) is the leading cause of cognitive decline in the elderly. Neuroimaging studies have shown that there are structural and functional connectivity abnormalities in patients with CSVD and are associated with cognitive impairment. Therefore, it is speculated that the changes of structural and functional connectivity may be an early imaging marker of CSVD-related cognitive impairment. This article reviews the significance of structural and functional connectivity in CSVD-related cognitive impairment.