Practice of neonatal capillary leakage syndrome / 中华实用儿科临床杂志

ABSTRACT

Capillary leak syndrome( CLS)is a group of clinical syndromes which caused by various causes of capillary endothelial damage,increased vascular permeability,resulting in a large amount of plasma protein infiltration into the interstitial space. It is one of the common critical cases in Neonatal Intensive Care Unit. As the complicated pathogenesis,blurred clinical stage and often neglected due to other complications,clinical treatment of CLS is difficult. Currently,there is no uniform diagnostic criteria,and the diagnosis is mainly based on clinical manifestation and labora-tory examination. The treatment of it is empiric but no specific treatment. Primary disease treatment and fluid manage-ment are the critical parts of the treatment of CLS. Now,the etiology,pathogenesis,clinical diagnosis and treatment of the disease were explained combined with the domestic and foreign literature and clinical diagnosis and treatment prac-tices,which aims to improve clinicians′understanding of the disease and the level of clinical diagnosis and treatment.