Relationship between serum CysC level and incidence of MACE in ACS patients after PCI ／ / 心血管康复医学杂志

ABSTRACT

To observe major adverse cardiovascular events (MACE) incidence rate in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI) , and explore relationship between serum level of cystatin (Cys) C and incidence of MACE in ACS patients after PCI .Methods: Clinical data of 374 ACS pa‐tients undergoing PCI in our hospital were retrospectively analyzed .Multivariate Logistic regression was used to ana‐ lyze risk factors for MACE within one year after PCI in ACS patients .Results: Among the 374 patients , incidence rate of MACE within one year after PCI was 22.99% (86／374).Multivariate Logistic regression analysis indicated that age＞72.6 years , diabetes mellitus , low density lipoprotein cholesterol (LDL‐C)＞3.38 mmol／L and CysC＞1.53mg／L were independent risk factors for incidence of MACE within one year after PCI in ACS patients (OR＝1.550～4. 723 , P＜0. 05 or ＜0.01) , while perioperative intensive statin therapy and perioperative tirofiban appli‐cation were its independent protective factors (OR ＝ 0.672 , 0. 596 , P＝ 0. 001 both ).Conclusion: Incidence of MACE after PCI in ACS patients is a result caused by multiple factor synergy .Preoperative elevated CysC level is closely associated with incidence of MACE after PCI , which calls for clinical attention .