Study on the influence of weakness on perioperative complications of thyroid, breast and hernia surgery in general surgery / 中国医师进修杂志

ABSTRACT

Objective To investigate the effect of weakness on perioperative complications of thyroid, breast and hernia surgery in general surgery. Methods Patients receiving thyroid breast surgery in Liaoning Provincial People′s Hospital were randomly selected from May 2014 to May 2017. The demographic variables of each patient were recorded, and the demographic variables were stratified. Each group of people was scored with a weakness index (mFI), with complications and serious complications as the dependent variables, and the demographic variables and mFI scores were used as covariates. Cox proportional hazard regression analysis of covariates and dependent variables was performed, the covariates were stratified, and risk factors between subgroups were compared. Results A total of 1 408 patients were eligible for inclusion in the above inclusion criteria. The female population was 801, with an average age of (59.7 ± 11.6) years, an average body mass index (BMI) of (28.7 ± 7.4) kg/m2. Compared with those in low mFI, the risk of complications and serious complications increased significantly (P <0.01) in moderate mFI ( HR=1.60, HR=2.10), and high mFI ( HR=3.36, HR=3.96). Patients with≥80 years old ( HR=1.22, HR=1.33) had a significant increase in the risk of postoperative complications and serious complications ( P < 0.05). Long-term dialysis ( HR=2.20, HR=2.13), long-term application of glucocorticoids ( HR=1.51, HR=2.27) patients had significant risk of complications and serious complications ( P < 0.01). Local anesthesia monitor ( HR=0.63, HR=0.67) reduced the risk of postoperative complications and serious complications (P<0.05). The risk of complications and serious complicationsin patients receiving hernia repair with moderate mFI ( HR=1.88, HR=2.01) and high mFI ( HR=2.12, HR=2.80) was significantly higher than that in patients with lower mFI ( P<0.01). The risk of complications and serious complications in patients of breast cancer with moderate mFI ( HR=1.76, HR=2.43) and high mFI ( HR=1.97, HR=2.38) was significantly higher than that in patients of breast cancer with low mFI ( P<0.01). Patients of thyroid cancer with a high mFI ( HR=6.38) showed a significantly higher risk of postoperative complications, compared with those with a low mFI (P<0.01). Conclusions For patients undergoing surgery for hernia, breast cancer, and thyroid cancer, weakness is associated with perioperative complications.