Risk factors of stress-induced upper gastrointestinal hemorrhage in acute cerebral infarction / 中国神经精神疾病杂志

ABSTRACT

Objective To explore risk factors for upper gastrointestinal bleeding in acute cerebral infarction. Method We enrolled continuously a total of 350 patients with acute cerebral infarction. Among them, 33 cases occurred upper gastrointestinal bleeding, accounting for 9.4%, and 317 cases without upper gastrointestinal bleeding, accounting for 90.6%. The incidence of various risk factors was compared between the two groups, and the independent risk factors of stress upper gastrointestinal bleeding were finally determined. Results National Institute of Health stroke scale (NIHSS) was significantly higher in the upper gastrointestinal bleeding group than in the control group [20 (2,32) vs. 5 (0,31)](P<0.001). The incidence of upper gastrointestinal bleeding was significantly increased in patients with posterior circulation infarct (POCI) (36.4% vs. 16.7%) and bilateral infarction (33.3% vs. 8.9%) (P<0.01). Only high NIHSS (OR=1.256, P<0.001) and bilateral infarction (OR=9.452,P<0.001) were independent risk factors for upper gastrointestinal bleeding in acute cerebral infarction. Conclusion More attention should be paid to patients with high NIHSS and bilateral infarction to avoid the occurrence of upper gastrointestinal hemorrhage, thereby reducing the negative influence on the prognosis of patients with cerebral infarction.