A Case of Immune Reconstitution Inflammatory Syndrome in AIDS-related Progressive Multifocal Leukoencephalopathy after Antiretroviral Therapy / 감염과화학요법
Infection and Chemotherapy
;
: 198-202, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-75397
ABSTRACT
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system due to JC virus. In acquired immunodeficiency syndrome (AIDS) patients, JC virus infects myelin-producing oligodendrocytes causing a non-inflammatory lytic reaction leading to demyelination and brain death. We herein report a case of a 56-years-old AIDS man who developed immune reconstitution inflammatory syndrome and died while undergoing highly active antiretroviral therapy. In this patient, the PML involved the brainstem, causing mental confusion followed by recurrent aspiration, adult respiratory distress syndrome, and eventually to early death.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Síndrome do Desconforto Respiratório
/
Morte Encefálica
/
Tronco Encefálico
/
Sistema Nervoso Central
/
Oligodendroglia
/
Síndrome da Imunodeficiência Adquirida
/
Leucoencefalopatia Multifocal Progressiva
/
Doenças Desmielinizantes
/
Vírus JC
/
Terapia Antirretroviral de Alta Atividade
Limite:
Humanos
Idioma:
Inglês
Revista:
Infection and Chemotherapy
Ano de publicação:
2010
Tipo de documento:
Artigo
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