Features and relevant factors concerning the ecological executive function of patients with benign epi-lepsy children with centrotemporal spikes / 中华行为医学与脑科学杂志

ABSTRACT

Objective To explore features and relevant factors affecting the ecological executive function in benign epilepsy children with centrotemporal spikes(BECT). Methods The behavior rating in-ventory of executive function (BRIEF) parental questionnaires were used to evaluate the executive function of 50 children with BECT (BECT group) and 50 normal children (control group) matched with BECT group (sex,age,education years). The differences of ecological executive function between the two groups were compared. Results (1)In BECT group,the scores of global executive composite (GEC),behavioral regula-tion index (BRI) and metacognition index (MI) ((51. 64±10. 30),(49. 02±8. 98),and (52. 78±10. 92), respectively) were significantly higher than those of the control group ((45. 70± 6. 55),(44. 96± 5. 35), (46. 72±6. 96),respectively,t=3. 440,2. 747,3. 309, all P<0. 05). Meanwhile,in BECT group,inhibit ((49. 90±10. 62),initiate (51. 76±11. 90),and working memory index scores (55. 58±10. 95) were also higher than those of the control group (44. 94± 6. 05,43. 74± 7. 63,47. 54± 7. 15,respectively,t=2. 870, 4. 014,4. 345, all P<0. 05). ( 2) Patients' condition had a negative predictive effect on inhibition ( β= -8. 926,P=0. 002),BRI ( β=-5. 422, P=0. 025), working memory ( β=-4. 980, P=0. 008), MI ( β=-4. 962,P=0. 034)and total score of scale( β=-6. 164,P=0. 004); attack times had a positive predictive effect on BRI(β=2. 555,P=0. 002),task initiation( β=7. 471,P<0. 01),working memory(β=5. 384,P<0. 01),MI (β=4. 726,P<0. 01) and total score of scale(β=4. 221,P<0. 01). Conclusion Children with BECT have ecological executive dysfunction. The number of epileptic seizures and the control of the disease are the main factors affecting the ecological executive function.