Advances in the pathogenesis and prediction models after intravenous thrombolysis secondary hemorrhagic transformation / 中国医师杂志

ABSTRACT

Intravenous thrombolysis is one of the most effective methods for the treatment of acute cerebral infarction.However,secondary hemorrhagic transformation after thrombolysis is a serious complication.Many studies have shown that hypofibrinemia and severe damage to the blood-brain barrier are important causes of this result.Bleeding after thrombolysis is not caused by a single factor.Foreign countries have more predictive research models for hemorrhagic transformation.Various research results have their own advantages and disadvantage.Domestic research is still scarce.This article reviews the pathogenesis,classification and prediction models of hemorrhagic transformation after intravenous thrombolysis.