Clinical study of percutaneous microwave ablation of uterine myometrium benign lesions / 中国医师杂志

ABSTRACT

Objective To study the clinical value of percutaneous microwave ablation of uterine myometrium benign lesions.Methods 100 cases of patients with benign lesions of myometrium in our hospital from January 2016 to January 2017 were enrolled in the study.According to the treatment methods,they were divided into observation group (percutaneous microwave ablation,n =50) and control group (uterine artery embolization,n =50).Relevant perioperative indicators,postoperative complications,hemoglobin (Hb),serum carbohydrate antigen 125 (CA125),menstrual status and follow-up results were observed in both groups.Results The operative time and ambulation time were significantly shortened in observation group (P ＜ 0.05).The postoperative adverse reaction rates in observation group and control group were 44.00％ and 100.00％ respectively (P ＜ 0.05),and the 1-year recurrence rates were 4.00％ and 12.00％ (P ＞0.05).After 1 month and 3 months of treatment,the menstrual period,menstrual volume and dysmenorrhea degree score were gradually decreased in the two groups,and the differences withingroups were significant (P ＜ 0.05).Compared with the corresponding time points of the control group,the level of each index in the observation group was lower,and there was significant difference between the two groups.At 3 months and 12 months after operation,the level of Hb in the two groups was gradually increased while the serum CA125 concentration was gradually decreased (P ＜ 0.05).Compared with the control group at each time point,the level of each index was better in observation group (P ＜ 0.05).At 6 months and 12 months after operation,the uterus volume and fibroid volume in the two groups were gradually decreased (P ＜ 0.05).Compared with the control group at each time point,the uterus volume and fibroid volume were smaller in observation group (P ＜ 0.05).Conclusions Microwave ablation has high safety in the treatment of benign lesions of myometrium,and it has the advantages of few postoperative complications,quick recovery and definite efficacy.Thus it is worthy of clinical promotion.