Analysis of clinical characteristics and inpatient adverse events of elderly patients with Stanford A type of aortic dissection / 中国中西医结合急救杂志

ABSTRACT

Objective To illustrate the clinical characteristics of elderly patients with Stanford type A aortic dissection and to discuss the incidence of such inpatients' adverse events. Methods A retrospective study was conducted, 588 patients with definite diagnosis of Stanford type A aortic dissection admitted to Beijing Anzhen Hospital of Capital Medical University from January 2013 to December 2015 were enrolled, and they were divided into an elderly group (≥60 years, 79 cases) and a non-elderly group (< 60 years, 509 cases). The differences of general clinical data, results of hospitalization-related examinations, medication for treatment, surgical intervention and inpatient adverse events between the two groups were compared. Results Compared with non-elderly group, the proportion of male, age, stature, body mass index (BMI), proportion of alcohol history, hemoglobin (Hb), incidence of acute liver failure in hospital in elderly group were decreased significantly [proportion of male 60.8% (48/79) vs. 80.6% (410/504), age (years)64.81±4.66 vs. 45.05±8.63, stature (cm) 169.41±8.09 vs. 173.39±7.59, BMI (kg/m2) 24.24±2.93 vs. 25.50±3.82, proportion of alcohol history 12.7% (10/79) vs. 22.4% (114/509), Hb (g/L) 122.62±21.14 vs. 128.42±23.44, incidence of acute liver failure 0 (0/79) vs. 5.3% (21/509), all P < 0.05], the proportion of diabetes history, proportion of cerebrovascular diseases, all-cause mortality in this hospital in elderly group were increased significantly [proportion of diabetes history 24.1% (62/79) vs. 8.8% (45/509), proportion of cerebrovascular diseases 6.3% (5/79) vs. 2.2% (11/509), all-cause mortality 16.5% (13/79) vs. 7.1% (36/509), all P < 0.05], and the left ventricular end diastolic internal diameter (LVEDD) in elderly group decreased significantly (mm 48.38±6.11 vs. 50.77±7.56, P <0.05). Conclusion The elderly patients with Stanford type A aortic dissection suffer from more complications and higher mortality, therefore, the risk consciousness should be strengthened for the senile patients and more attention should be paid on the prevention of the elderly inpatients' adverse events.