A Case of Squamous Cell Carcinoma Originating from Oral Lichen Planus / 대한피부과학회지

ABSTRACT

Oral lichen planus (OLP) is a relatively common chronic inflammatory disease of uncertain etiology. OLP lesions rarely undergo spontaneous remission and have the potential to undergo malignant transformation. The risk of malignant transformation in OLP is estimated to be between 0.4% and 5.3%; two clinical studies in Korea reported the frequency of malignant change as 2.9% and 2.85%. However, to the best of our knowledge, there has been no individual case report in the Korean dermatological literature to date regarding the malignant transformation of OLP. Herein, we report the case of a 77-year-old Korean woman with long-standing OLP that underwent transformation to oral squamous cell carcinoma. This is the first well-documented case report of squamous cell carcinoma that developed from OLP.