Matrix Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-1 levels in Exudative Pleural Effusions / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 517-521, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-75627
ABSTRACT
BACKGROUND:
The balances of the proteinases and antiproteinases system have been implicated in the pathogenesis of various exudative pleural effusions. The aim of this study was to examine the matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) levels in exudative pleural effusions.METHODS:
The study included 33 tuberculous effusions, 17 malignant, and 5 transudates. The pleural levels of MMP-1 and TIMP-1 were determined using a commercially available ELISA assay.RESULTS:
The group of tuberculous effusions showed higher pleural MMP-1 levels than the malignant and transudates. The pleural TIMP-1 levels of the tuberculous and malignant effusions were higher than the transudates.CONCLUSION:
Elevated pleural MMP-1 and TIMP-1 levels were found in tuberculous effusions.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peptídeo Hidrolases
/
Derrame Pleural
/
Ensaio de Imunoadsorção Enzimática
/
Inibidor Tecidual de Metaloproteinase-1
/
Metaloproteinase 1 da Matriz
/
Exsudatos e Transudatos
Idioma:
Coreano
Revista:
Tuberculosis and Respiratory Diseases
Ano de publicação:
2005
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS