Amazing structure of respirasome: unveiling the secrets of cell respiration
Protein & Cell
;
(12): 854-865, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-757378
ABSTRACT
Respirasome, a huge molecular machine that carries out cellular respiration, has gained growing attention since its discovery, because respiration is the most indispensable biological process in almost all living creatures. The concept of respirasome has renewed our understanding of the respiratory chain organization, and most recently, the structure of respirasome solved by Yang's group from Tsinghua University (Gu et al. Nature 237(7622)639-643, 2016) firstly presented the detailed interactions within this huge molecular machine, and provided important information for drug design and screening. However, the study of cellular respiration went through a long history. Here, we briefly showed the detoured history of respiratory chain investigation, and then described the amazing structure of respirasome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Relação Estrutura-Atividade
/
Química
/
Estrutura Quaternária de Proteína
/
Complexo de Proteínas da Cadeia de Transporte de Elétrons
/
História do Século XX
/
História do Século XXI
/
Transporte de Elétrons
/
História
/
Metabolismo
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Protein & Cell
Ano de publicação:
2016
Tipo de documento:
Artigo
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