The next-generation sequencing technology and application
Protein & Cell
;
(12): 520-536, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-757698
ABSTRACT
As one of the key technologies in biomedical research, DNA sequencing has not only improved its productivity with an exponential growth rate but also been applied to new areas of application over the past few years. This is largely due to the advent of newer generations of sequencing platforms, offering ever-faster and cheaper ways to analyze sequences. In our previous review, we looked into technical characteristics of the next-generation sequencers and provided prospective insights into their future development. In this article, we present a brief overview of the advantages and shortcomings of key commercially available platforms with a focus on their suitability for a broad range of applications.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Química
/
Perfilação da Expressão Gênica
/
Genômica
/
Nanoestruturas
/
Proteínas de Ligação a DNA
/
Pequeno RNA não Traduzido
/
Sequenciamento de Nucleotídeos em Larga Escala
/
Epigenômica
/
Métodos
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Protein & Cell
Ano de publicação:
2010
Tipo de documento:
Artigo
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