Efficacy of Taurolidine Irrigation in Primary Total Knee Arthroplasty
The Journal of Korean Knee Society
;
: 142-146, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-759318
ABSTRACT
PURPOSE:
Taurolidine is an antimicrobial agent that was originally used in the local treatment of peritonitis. The aim of this study was to evaluate the efficacy of taurolidine irrigation in primary total knee arthroplasty (TKA). MATERIALS ANDMETHODS:
All patients who underwent TKA at our institute from January 2015 to March 2017 were eligible. There were 300 patients in the taurolidine irrigation group and 300 patients in the control group. The patients in the taurolidine irrigation group were irrigated after implantation with a mix of 250 mL of taurolidine and 750 mL of normal saline. The patients in the control group were not irrigated after implantation. We compared postoperative C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and infection rate between groups.RESULTS:
The taurolidine irrigation group had a significantly lower CRP (5.39 mg/dL vs. 7.55 mg/dL; p<0.001) and ESR (53.21 mm/hr vs. 58.74 mm/hr; p=0.003) on postoperative day 3 after TKA, as compared with the control group. However, there was no difference between the two groups on postoperative days 6, 13, and 20. Periprosthetic joint infection occurred in one patient in the taurolidine irrigation group.CONCLUSIONS:
We believe that it is not necessary to use taurolidine for patients who undergo primary TKA.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peritonite
/
Artroplastia
/
Sedimentação Sanguínea
/
Proteína C-Reativa
/
Artroplastia do Joelho
/
Articulações
/
Joelho
Limite:
Humanos
Idioma:
Inglês
Revista:
The Journal of Korean Knee Society
Ano de publicação:
2018
Tipo de documento:
Artigo
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