Two Cases of Opioid-Induced Hyperalgesia in Cancer Patients Treated with Opioids for Pain Management / 한국호스피스완화의료학회지
Korean Journal of Hospice and Palliative Care
;
: 100-104, 2019.
Artigo
em Coreano
| WPRIM
| ID: wpr-759852
ABSTRACT
Opioids are important drugs for the management of severe cancer pain without a ceiling effect. However, opioid administration leads to dose-limiting complications including drowsiness, hallucinations, delirium, respiratory depression, cognitive impairment, seizure, myoclonus, and hyperalgesia. Opioid-induced hyperalgesia (OIH) is a paradoxical phenomenon as opioid exposure increases pain sensitivity. Reducing or stopping opioids, opioid rotation, or co-administration of N-methyl-D-aspartate (NMDA) antagonists have been suggested for the management of OIH. In this study, we report two clinical cases of successful management of OIH in cancer pain patients that were treated with opioids.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Insuficiência Respiratória
/
Convulsões
/
Fases do Sono
/
N-Metilaspartato
/
Transtornos Cognitivos
/
Delírio
/
Manejo da Dor
/
Alucinações
/
Hiperalgesia
/
Analgésicos Opioides
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Hospice and Palliative Care
Ano de publicação:
2019
Tipo de documento:
Artigo
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