Mycophenolate Mofetil Overdose Induced Ventricular Tachycardia in a Patient with Systemic Lupus Erythematosus / 대한내과학회지
Korean Journal of Medicine
;
: 455-458, 2019.
Artigo
em Coreano
| WPRIM
| ID: wpr-759954
ABSTRACT
Mycophenolate mofetil (MMF) is an immunosuppressive agent used to treat severe lupus, including lupus nephritis. Common adverse effects of MMF include gastrointestinal and hematological manifestations; however, cardiac toxicity in association with MMF has not been reported. We present a 21-year-old woman with lupus nephritis who developed ventricular tachycardia 2 hours after an overdose of MMF (34 g). Ventricular bigeminy was documented 12 hours after the MMF overdose. Transthoracic echocardiography showed no evidence of structural heart disease. The ventricular arrhythmia was successfully treated with potassium replacement, hydration, and cholestyramine. This case suggests that an overdose of MMF can induce ventricular tachycardia, and electrocardiogram monitoring is critical to identify this rare cardiac complication of MMF.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Arritmias Cardíacas
/
Potássio
/
Nefrite Lúpica
/
Ecocardiografia
/
Resina de Colestiramina
/
Taquicardia Ventricular
/
Eletrocardiografia
/
Cardiotoxicidade
/
Cardiopatias
/
Lúpus Eritematoso Sistêmico
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
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