Flavestin K, An Isoprenylated Stilbene from the Leaves of Macaranga recurvata Gage
Natural Product Sciences
;
: 244-247, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-760565
ABSTRACT
A new isoprenylated stilbene, flavestinK (1) together with two known isoprenylated stilbenes, flavestin B (2), flavestin G (3), and two isoprenilated flavanones, 4-O-methyl-8-isoprenylnaringenin (4) and 8-isoprenyl-5,7-dihydroxyflavanone (5) were isolated from the leaves of Macaranga recurvata Gage. All of the structures have been determined based on HRESIMS, 1D and 2D NMR spectral data. All of the isolated compounds were evaluated for their cytotoxicity against three human cancer cells (HeLa, T47D and WiDr). Compound 1 showed higher activity than doxorubicin against HeLa cells with IC₅₀ value of 13.1 µg/mL.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Estilbenos
/
Células HeLa
/
Doxorrubicina
/
Euphorbiaceae
/
Flavanonas
Limite:
Humanos
Idioma:
Inglês
Revista:
Natural Product Sciences
Ano de publicação:
2019
Tipo de documento:
Artigo
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